- P-ISSN 2233-4203
- E-ISSN 2093-8950
- P-ISSN2233-4203
- E-ISSN2093-8950
- ESCI, SCOPUS, KCI
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Global Histidine Phosphoproteomics in Human Prostate Cancer Cells
Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2020, v.11 no.3, pp.52-58
https://doi.org/10.5478/MSL.2020.11.3.52
(Kyungpook National University)
(Kyungpook National University)
(Kyungpook National University)
(Kyungpook National University)
(Kyungpook National University)
(Kyungpook National University)
(Kyungpook National University)
(Kyungpook National University)
(Kyungpook National University)
(Kyungpook National University)
(Kyungpook National University)
(Kyungpook National University)
(Kyungpook National University)
Gao,
Y., Kim,
D., Sung,
E., Tan,
M., Kwon,
T. G., Lee,
J. N., &
Lee,
S.
(2020). . , 11(3), 52-58, https://doi.org/10.5478/MSL.2020.11.3.52
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Abstract
Histidine phosphorylation (pHis) is increasingly recognized as an important post translational modification (PTM) in regulating cellular functions in eukaryotes. In order to clarify the role of pHis in mammalian cell signaling system, a global phos-phorylation study was performed in human prostate cancer cells, PC-3M, using a TiO 2 affinity chromatography. A total number of 307 pHis sites were identified on the 268 proteins among total identified 9,924 phosphorylation sites on 3,316 proteins. In addition, 22 pHis proteins were classified in enzyme category. This report provides the first database for the study of pHis in prostate cancer cells.
- keywords
- Histidine phosphorylation, TiO 2 -affinity chromatography, Mammalian cells, LC-MS
- 투고일Received
- 2020-07-18
- 수정일Revised
- 2020-09-03
- 게재확정일Accepted
- 2020-09-03
- 출판일Published
- 2020-09-30
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