Potentiometric Characteristics of Acidic Drug Selective Membrane Electrodes using Di-2-pyridyl ketone

안문규; 이동엽; 이재윤

오늘 하루 그만보기

P-ISSN1225-0163
E-ISSN2288-8985
SCOPUS, ESCI, KCI

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P-ISSN 1225-0163
E-ISSN 2288-8985

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Vol.16, No.4

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Potentiometric Characteristics of Acidic Drug Selective Membrane Electrodes using Di-2-pyridyl ketone

Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985

2003, v.16 no.4, pp.320-324

& (2003). Potentiometric Characteristics of Acidic Drug Selective Membrane Electrodes using Di-2-pyridyl ketone. , 16(4), 320-324.

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Abstract

Acidic drug selective electrodes based on metal(II)-di-2-pyridyl ketone-acidic drugs ternary complex as electroactive material were prepared. The metal ions, $Fe^{2+}$, $Co^{2+}$, $Ni^{2+}$, $Cu^{2+}$ were used. Nitrophenyl ether series were used as plasticizers. The electrodes exhibit a fast stable and linear response for $5{\times}10^{-5}{\sim}10^{-3}mol/L$ mefenamic acid (MA) in borate buffer solution (pH 8.9) and ibuprofen(Ib) in phosphate buffer solution (pH 7.0). The recovery test for mefenamic acid and ibuprofen using standard addition method were 99.0% and 98.4% with relative standard deviation of 2.4% and 2.6% respectively.