- ENGLISH
- P-ISSN2951-0333
- E-ISSN2951-0597
대사이상지방간질환을 동반한 자가면역간염 환자에서의 세마글루티드 사용 2례
Two Cases of Semaglutide Use in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease and Autoimmune Hepatitis
최준혁(Joon Hyuk Choi) (영남대학교 의과대학 병리학교실)
Abstract
Concomitant metabolic dysfunction-associated steatotic liver disease (MASLD) and autoimmune hepatitis (AIH) complicates diagnosis, even when liver biopsy is performed. Furthermore, corticosteroid treatment can exacerbate steatosis, often impeding a complete biochemical response. As a result, assessing the histological response remains challenging, even when performing follow-up liver biopsies. Although implementing lifestyle modifications can normalize liver enzyme levels, most patients are unable to achieve adequate weight loss. In contrast, the use of semaglutide facilitated a more effective improvement in liver tests when compared to general lifestyle modifications, thereby enabling clearer assessment of liver function deterioration due to MASLD. Here, we report two cases of a diagnostic trial using semaglutide in patients with MASLD combined with AIH.
- keywords
- Steatohepatitis, Hepatitis, Autoimmune, Metabolic syndrome, Steroids
- 투고일Received
- 2025-11-26
- 수정일Revised
- 2025-12-16
- 게재확정일Accepted
- 2025-12-17
- 출판일Published
- 2025-12-31
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