- P-ISSN 1225-0163
- E-ISSN 2288-8985
- P-ISSN1225-0163
- E-ISSN2288-8985
- SCOPUS, ESCI, KCI
Article Detail
Home > Article Detail
A study of the metabolites for 7-keto-DHEA-acetate in human urine
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
2004, v.17 no.4, pp.337-346
&
(2004). A study of the metabolites for 7-keto-DHEA-acetate in human urine. , 17(4), 337-346.
Abstract
7-keto-dehydroepiandrosterone-acetate (7-keto-DHEA-acetate) is an anabolic steroids, and we studied basically to the metabolites of it after human dosing. We tested the matrix effect from human urine to detect the 7-keto-DHEA-acetate. And LC/ESI/MS and GC/MSD was used to detect the metabolites in dosed urine. We found the some unknown compound from dosed urine (M1, M2, M3, M4 and M5), and from these results, we supposed that these compounds have the more than 3 hydroxyl and/or ketone group. Metabolite M1 was supposed that molecular weight is 302 and 3-,17- diketone and 7-hydroxyl compound(7-OH-androstendione). Metabolite M2 was supposed that the molecular weight was same to M1 and 7-,17- diketone and 3-hydroxyl compound(7-keto-DHEA).
- keywords
- 7-keto-dehydroepiandrosterone-acetate, metabolites, human dosed urine, metabolite M1, metabolite M2, LC/ESI/MS, GC/MS
Other articles from this issue
- Determination of oxymatrine in Sophora Radix by High Performance Liquid Chromartography
- Comparison of Static and Dynamic Solvent Extraction of Polychlorinated Dibenzofurans from Fly Ash
- Determination of trace actinide(Am, Pu, Th, U) using alpha spectrometry and neutron activation analysis
- Trace impurities analysis of the electronic polymer resins by neutron activation analysis
- The classification of ballpoint pen inks in Questioned Documents by using VSC and SERRS
- A study on the derivatization technique for tamoxifen metabolites in human urine by gas chromatography/mass spectrometry
- A study of the metabolites for 7-keto-DHEA-acetate in human urine
- Accumulation Levels and Distribution Characteristics of Polychlorinated Biphenyls in Crucians and Leopard Frogs from the Nakdong River Basin
- EPMA Analysis of Inter-reaction Layer in Irradiated U3Si-Al Fuels
- Determination of Heavy Metal in Polyurethane by New Digestion Method and ICP-AES
- more
Recommanded Articles
This website recommended the use the Chrome browser for journal website.