Potentiometric performances of polymer membtane electrode based on cyclosporin
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
2005, v.18 no.6, pp.490-494
(2005). Potentiometric performances of polymer membtane electrode based on cyclosporin. , 18(6), 490-494.
Abstract
The main component governing selectivity in ion-selective electrodes and optodes is the ionophore. For this reason, a member of natural products that possess selective ion-binding properties have long been sought after. By applying this principle, the performance of cyclosporin used as neutral carriers for calcium selective polymeric membrane electrode was investigated. The calcium ion-selective electrode based on cyclosporin gave a good Nernstian response of 26.6 mV per decade for calcium ion in the activity range $1{\times}10^{-6}M$ to $1{\times}10^{-2}M$. The optimized calcium ion-selective electrode displayed very comparable selectivity for $Ca^{2+}$ ion against alkali and alkaline earth metal ions, $Na^{2+}$, and $Mg^{2+}$ in particular.
- keywords
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cyclosporin,
ionophore,
<TEX>$Ca^{2+}$</TEX>,
ion-selective electrode