Analysis of didecydimethylammonium chloride (DDAC) aerosol in inhalation chamber

양정선; 최성봉; 박상용; 이성배

doi:10.5806/AST.2012.25.5.307

오늘 하루 그만보기

P-ISSN1225-0163
E-ISSN2288-8985
SCOPUS, ESCI, KCI

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P-ISSN 1225-0163
E-ISSN 2288-8985

e-Submission

Vol.25, No.5

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Analysis of didecydimethylammonium chloride (DDAC) aerosol in inhalation chamber

Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985

2012, v.25 no.5, pp.307-312

https://doi.org/10.5806/AST.2012.25.5.307

& (2012). Analysis of didecydimethylammonium chloride (DDAC) aerosol in inhalation chamber. , 25(5), 307-312, https://doi.org/10.5806/AST.2012.25.5.307

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Abstract

To perform inhalation toxicity test by using experiment animals, we set up an analytical method to monitor didecyldimethylammonium chloride (DDAC) in aerosol nebulized into inhalation chambers by ion chromatography. DDAC was adsorbed by XAD-2 resin and analyzed with conductivity detector. Recovery of DDAC desorbed by acetonitrile from XAD adsorbent was 87.8%. The method detection limit (MDL) and the limit of quantitation (LOQ) were 2.97 μg/m3 and 8.92 μg/m3, respectively. Repeatability was calculated as RSD 7.8% in the range of 0~20 μg/mL. Time needed to analyze a sample was less than 5 minutes. Therefore, the analysis of DDAC by ion chromatography was practically useful in monitoring DDAC in inhalation chambers with rapidity and sensitivity manner to perform inhalation toxicity test using experimental animals.