Ion-Selective Electrodes for the Determination of Alverine
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
1995, v.8 no.1, pp.79-84
Lee, Eun-Yup
Kim, Ki-Myo
Kim, Sung-Jin
Hur, Moon-Hye
Ahn, Moon-Kyu
Lee,
E., Kim,
K., Kim,
S., Hur,
M., &
Ahn,
M.
(1995). Ion-Selective Electrodes for the Determination of Alverine. , 8(1), 79-84.
Abstract
Ion-selective poly(vinyl chloride) membrane electrodes for the determination of the anticholinergic drug alverine in pure substances is described. Ion-pair complex of alverine with anionic counter ion acid red 97 is investigated as electroactive compound for the electrode membrane. On the optimal composition of membrane, its slope was 55.35mV/decade, relative standard deviation was 0.61 and lower limit of linear range was $1.0{\times}10^{-5}M$. The observed potentiometric selectivity coefficient was -2.625 toward methylephedrine and -2.216 toward histidine. We can got the stable potential at pH 7.0~4.0. Response time was 20~30 seconds for solutions${\leq}10^{-4}M$, about 10 seconds for solutions ${\geq}10^{-4}M$ of these compounds.
- keywords
-
Ion-selective electrode,
anionic counter ion,
acid red 97,
alverine