Purpose: This study explores the impact of e-commerce on the development of the global and Indonesian digital economy, emphasizing its role in economic growth, empowering Micro, Small, and Medium Enterprises (MSMEs), and addressing challenges like cybersecurity threats and digital inequality. Research Design, Data, and Methodology: A qualitative approach was employed, utilizing a systematic literature review based on PRISMA guidelines, analysing 48 studies from 2018 to 2024. A bibliometric analysis with VOSviewer was conducted to examine research trends and thematic connections. Results: The findings indicate that e-commerce enhances market access and operational efficiency for MSMEs, particularly in developing countries. Success in the digital economy is linked to effective digital marketing strategies and technological innovations such as big data analytics and social media. Nevertheless, issues like cybersecurity risks and digital literacy gaps pose significant challenges, especially in rural areas. The bibliometric analysis reveals strong relationships between government policies, technological advancements, and stakeholder collaboration in building a resilient e-commerce ecosystem. Conclusion: The research underscores the importance of inclusive policies, enhanced digital literacy, and robust cybersecurity measures for sustainable digital economic growth. Targeted support for MSMEs is vital for their digital transformation, necessitating a comprehensive approach that combines policy, technology, and education to maximize e-commerce's potential.
