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Journal of the Korean Association of Oral and Maxillofacial Surgeons

  • P-ISSN2234-7550
  • E-ISSN2234-5930
  • SCOPUS, KCI, ESCI

ISSN : 2234-7550

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Vol.51 No.2

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Mandibular metastasis of papillary thyroid carcinoma: a case report and systematic literature review

Journal of the Korean Association of Oral and Maxillofacial Surgeons / Journal of the Korean Association of Oral and Maxillofacial Surgeons, (P)2234-7550; (E)2234-5930
2025, v.51 no.2, pp.73-79
https://doi.org/10.5125/jkaoms.2025.51.2.73
Shin Yootaek (Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry, Seoul, Korea)
Kim Hyounmin (Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry, Seoul, Korea)
Yang Solbin (Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry, Seoul, Korea)
Han Seung-Yong (Department of Oral Pathology, Yonsei University College of Dentistry, Seoul, Korea)
Cho Eunae Sandra (Department of Oral Pathology, Yonsei University College of Dentistry, Seoul, Korea)
Kim Dongwook (Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry, Seoul, Korea)
Kim Hyung Jun (Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry, Seoul, Korea)
Shin, Y. , Kim, H. , Yang, S. , Han, S. , Cho, E. S. , Kim, D. , & Kim, H. J. (2025). Mandibular metastasis of papillary thyroid carcinoma: a case report and systematic literature review. , 51(2), 73-79, https://doi.org/10.5125/jkaoms.2025.51.2.73

Abstract

In this paper, we systematically review the literature on papillary thyroid carcinoma (PTC) metastasis to the mandible. This is a rare oc-currence, especially in young, asymptomatic patients. We propose appropriate surgical and adjuvant therapy guidelines based on our findings. A systematic PubMed search (up to July 2023) identified 10 eligible cases of papillary or follicular thyroid carcinoma with metastasis to the mandible. Studies of patients with different histologic types or without confirmed distant metastasis were excluded. A rare case of PTC metastasizing to the mandible in a young male highlights an unusual presentation. Surgical treatment of both primary and metastatic sites, along with aggressive adjuvant therapy after surgery, had a positive impact on survival.

keywords
Thyroid neoplasm, Papillary carcinoma, Neoplasm metastasis, Mandible

Journal of the Korean Association of Oral and Maxillofacial Surgeons

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