Characterization of Adsorbents for the Simultaneous Solid-Phase Extraction of Trace $\beta$-Blockers from Biological Samples
Analytical Science and Technology / Analytical Science and Technology, (P)1225-0163; (E)2288-8985
1993, v.6 no.4, pp.375-381
Kim, Kyoung Rae
Kim, Do Jeong
Kim,
K. R., &
Kim,
D.
J.
(1993). Characterization of Adsorbents for the Simultaneous Solid-Phase Extraction of Trace <TEX>$\beta$</TEX>-Blockers from Biological Samples. , 6(4), 375-381.
Abstract
The efficiencies of four different solid absorbents were evaluated for the simultaneous solid-phase extraction of six ${\beta}$-blockers from biological sample. Chromosorb 107 using methanol as the eluting solvent gave the highest solid-phase extraction yield. From the breakthrough studies of ${\beta}$-blockers, the excellent sorption and desorption properties of the Chromosorb 107 column were verified. The usefulness of Chromosorb 107/methanol was examined for the simultaneous solid-phase extraction of the ${\beta}$-blockers from serum in the concentration range of 2~8ppm.
- keywords
-
solid-phase extraction,
<TEX>${\beta}$</TEX>-blockers,
Chromosorb 107/methanol,
breakthrough curve,
serum