- P-ISSN 2233-4203
- E-ISSN 2093-8950
- P-ISSN2233-4203
- E-ISSN2093-8950
- ESCI, SCOPUS, KCI
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Characterization of N-Alkylamides of Spilanthes acmella var calva by Using High Performance Liquid Chromatography Electrospray Ionization Ion Trap Mass Spectrometry
Mass Spectrometry Letters / Mass Spectrometry Letters, (P)2233-4203; (E)2093-8950
2025, v.16 no.2, pp.31-41
https://doi.org/10.5478/10.5478/MSL.2025.16.2.31
(Faculty of Science, Nepal Academy of Science and Technology)
(Central Department of Chemistry, Tribhuvan University)
(H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi)
(H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi)
(H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi)
(H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi)
(Central Department of Chemistry, Tribhuvan University)
(H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi)
(H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi)
(H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi)
(H.E.J. Research Institute of Chemistry, International Center for Chemical and Biological Sciences, University of Karachi)
Shyaula,
S. L., Acharya,
A., Choudhary,
M. I., Musharraf,
S. G., Maharjan,
R., &
Ali,
A.
(2025). Characterization of N-Alkylamides of Spilanthes acmella var calva by Using High Performance Liquid Chromatography Electrospray Ionization Ion Trap Mass Spectrometry. , 16(2), 31-41, https://doi.org/10.5478/10.5478/MSL.2025.16.2.31
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Abstract
Spilanthes acmella var calva popularly known as ‘Marauti’ in Nepal, are widely used by different communities as the food ingredients in their traditional cuisines. It displays a unique tingling sensation mainly due to N-alkylamides when applied to mucosal surfaces. Spilanthes served as a remedy for alleviating toothache, throat infections and other oral ailments. N- Alkylamide profilings of Spilanthes extracts were performed using a gradient reversed phase high performance liquid chroma- tography/ electrospray ionization ion trap mass spectrometry (HPLC/ESI-MS) method. A total of 33 peaks were analyzed and 16 N-alkylamides were identified. Seven compounds (1, 5, 6, 8, 15, 16 and 25) were N-isobutylamides and nine compounds (4, 7, 10, 11, 12, 14, 17, 18 and 20) were 2-phenylethylamides.
- keywords
- Spilanthes acmella, N-Alkylamides, N-Isobutylamides, 2-Phenylethylamide, Ion trap
- Received
- 2025-02-20
- Revised
- 2025-04-29
- Accepted
- 2025-05-15
- Published
- 2025-06-30
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