Purpose: This study aimed to identify and prioritize core nursing skills required for clinical practice education in Cambodia and to inform improvements in competency-based training programs. Research design, data and methodology: A descriptive cross-sectional survey was conducted using purposive and snowball sampling. Data were collected from 82 stakeholders, including senior nursing students, practicing nurses, faculty members, and nursing education-related personnel. The survey instrument consisted of 11 nursing skill domains derived from domestic and international protocols. Skills were rated on a five-point Likert scale for importance, urgency, and applicability. Educational priorities were classified using an Importance–Urgency Analysis framework combined with an Eisenhower matrix. Results: Overall applicability of core nursing skills was high, but priorities varied across domains. Nutrition nursing, examination and monitoring, emergency nursing, and perioperative nursing were identified as high-priority areas requiring immediate and intensive educational intervention due to high importance and urgency. Other domains showed relatively lower priority, indicating feasibility for phased implementation and field-based learning. Conclusions: The findings suggest that current nursing practice education in Cambodia does not adequately reflect clinical demands. Curriculum reform focusing on high-priority skills, expanded simulation-based education, improved training infrastructure, and standardized guidelines is recommended to strengthen nursing capacity and improve quality of care.