ISSN : 1229-0653
The purpose of this study was to investigate the effects of early isolated rearing on the later susceptibility to stress ulcers. A/J strain mice were reared individually after weaning. The various stress-ulcer paradigms were employed to test isolation effects. Isolated mice showed less susceptibility to the ulcers in various stress paradigms. The intensity of stress being increased, the ulcer was more developed in all animals. This results suggest that the isolation-induced behavioral and physiological changes contributed to less susceptibility to stress-ulcers.